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Development and validation of a short questionnaire in community acquired pneumonia
1 Department of Internal Medicine, Division of Infectious Diseases, Tropical Medicine, and AIDS, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands 2 Department of Clinical ...
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Lung volume reduction surgery (LVRS) for chronic obstructive pulmonary disease (COPD) with underlying severe emphysema
BACKGROUND Lung volume reduction surgery (LVRS) has recently re-emerged as a surgical option for the treatment of end stage chronic obstructive pulmonary disease (COPD) due to underlying severe ...
thorax.bmj5d
Management of malignant pleural effusions
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thorax.bmj5d
Lung cancer, genetic predisposition and smoking: the Nordic Twin Study of Cancer
Background We aimed to disentangle genetic and environmental causes in lung cancer while considering smoking status. Methods Four Nordic twin cohorts (43 512 monozygotic (MZ) and 71 895 same sex ...
thorax.bmj5d
Serum carotenoids, vitamins A and E, and 8 year lung function decline in a general population
Background: Oxidative stress is thought to have a major role in the pathogenesis of airway obstruction. A study was undertaken to determine whether subjects with low levels of antioxidants (serum ...
thorax.bmj5d
Genome-wide association study across five cohorts identifies five novel loci associated with idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a chronic lung condition with poor survival times. We previously published a genome-wide meta-analysis of IPF risk across three studies with independent ...
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Beyond borders: cystic fibrosis survival between Australia, Canada, France and New Zealand
Background Life expectancy for people with cystic fibrosis (CF) varies considerably both within and between countries. The objective of this study was to compare survival among countries with ...
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The incremental shuttle walking test in elderly people with chronic airflow limitation
1 Department of Geriatric Medicine, Royal United Hospital Bath NHS Trust, Bath, UK 2 Department of Respiratory Medicine, Glenfield Hospital, Leicester, UK 3 Department of Respiratory Medicine, ...
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IL-25 drives remodelling in allergic airways disease induced by house dust mite
Background Overexpression of the transforming growth factor β family signalling molecule smad2 in the airway epithelium provokes enhanced allergen-induced airway remodelling in mice, concomitant with ...
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Associations of pulmonary microvascular blood volume with per cent emphysema and CT emphysema subtypes in the community: the MESA Lung study
Background Pulmonary microvasculature alterations are implicated in emphysema pathogenesis, but the association between ...
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β-Actin and GAPDH housekeeping gene expression in asthmatic airways is variable and not suitable for normalising mRNA levels
1 Department of Respiratory Medicine, Alfred Hospital and Monash University Medical School, Melbourne 3181, Australia 2 Department of Epidemiology and Preventive Medicine, Alfred Hospital and Monash ...