A multi-vehicle crash has closed part of Interstate 81 in Franklin County near the Maryland line, traffic maps show.
More closures of multiple lanes and exit ramps will take place overnight for work associated with the 10 Bridges Project.
The northbound lanes of Interstate 97 are closed late Monday morning after a tractor-trailer turned onto its side in the Millersville area.
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Recent years have seen an increase in traffic congestion and safety concerns brought on by warehouses and other development pressures affecting Route 233.