Kimmel also reacted to Trump’s appointment of Fox & Friends Weekend co-host Pete Hegseth as Secretary of Defense, which has sparked outrage from critics. “There’s nothing more intimidating than a morning talk show host. It’s why Regis was so valuable to JFK during the Cuban Missile Crisis,” Kimmel joked.

Kimmel played a supercut video of all the insults Trump hurled at Rubio during the 2016 Republican primary, when the two were campaign rivals, including dismissing the senator as “Liddle Marco,” a “choke artist,” and a “total lightweight” with a “little mouth” who sweats profusely.

Puppy-killing Kristi Noem "shouldn't be in charge of a Pet Smart, let alone Homeland Security," quipped the late-night host

Following the 2024 election of U.S. President-elect Donald Trump to a second term, claims emerged on social media that late-night host Jimmy Kimmel, a longtime Trump critic, would be canceling his show, "Jimmy Kimmel Live!", and moving to Canada on Inauguration Day: